www.apicmo.com www.cofttek.com www.aasraw.com www.phcoker.com www.scienceherb.com www.cmoapi.com www.apicdmo.com, No. 5, pp.1013-1024.Â Many product types can deliver vitamin C to the skin, including gels, serums and powders. Vitamin C is an excellent supplement for your skincare. Melanin is the molecule responsible for givingÂ skin color or pigment, and the uneven production of melanin results in pigmentation areas on the surface. L-ascorbic acid is one of the two forms of vitamin C found in nature and is the most biologically active, meaning it is the most beneficial. For instance, ethyl ascorbic acid vs magnesium ascorbyl phosphate, which almost work in the same way in brightening your skin and as an anti-aging supplement, can make it hard for you to choose the right supplement. If you want a highly potent yet gentle … Lane, M., Iliopoulos, F., Moore, D. J., Lucas, R. A., & Sil, B. These can range from pregnancy or melasma, hormonal imbalance and sun damage to genetic predispositions, injury or inflammation. However, the skin is often the last organ to receive vitamin C and does not receive it at the concentrations required to affect the skin in any significant way. Vitamin C works to reduce the visibility of pigmentation through inhibition of the enzyme responsible for producing melanin in the skin. 4, is. This can affect the health of the skin mantle barrier, interact with other products and hasten the aging process.Â, L-ascorbic acid will only stay active in skincare products for a short period once opened. These two characteristics mean that L-ascorbic acid will readily bind to water molecules, making it hard for the molecule to pass through the skinâs hydrophobic layers.Â, Reducing the pH of a product to less than 3.5 orÂ less makes it more acidic, allowing for L-ascorbic acid to penetrate deeper and be stable for longer.Â However, reducing the pH of the product may lead to sensitization of the skin, as the natural pH of the skin is around. 24. In a review conducted by the, , evidence indicated that tetrahexyldecyl ascorbate is more stable in solution, less irritating and able to penetrate deeper into the skin, making it a promising vitamin C treatment.Â. Ethyl ascorbic acid is the most effective among the three in boosting collagen synthesis and lightening skin, with over 80% metabolized to pure L-ascorbic acid. Both the topical and oral form are often used alongside other drugs and supplementation.Â, References:Al-Niami, F & Chiang, N 2017. âTopical Vitamin C and the Skin: Mechanisms of Action and Clinical Applicationsâ, The Journal of Clinical and Aesthetic Dermatology, vol. 418-425.Â, Pinnell, S, Yang, H, Omar, M, Monteiro-Riviere, N, DeBuys, H, Walker, L, Wang, Y & Levine, M 2001. âTopical L-ascorbic Acid: Percutaneous Absorption Studiesâ, Dermatol Surg, vol.27, is. It is responsible for protecting the skinâs deeper layers from damage, allergens, bacteria and moisture loss. This molecule signals the production of collagen and is responsible for signaling to the cell that collagen is needed. As we age, collagen production decreases. Concentration is another critical element when considering which L-ascorbic acid products would best suit your needs. The two compounds might be different, but they deliver the same results to the user. This lack of information regarding concentration tends to occur with formulations utilizing kakadu plum, hibiscus or plant-based vitamin C sources. Environmental factors such as radiation from the sun, UVA and UVB, pollution, smoking, and diet can put the skin in a state of oxidative stress. ELAN is a vitamin C serum that includes a 30 percent concentration of ethylated L-ascorbic acid along with a few other antioxidant ingredients — superoxide dismutase, selenium and zinc. 819.Â. Vitamin C acts as a cofactor or a helper molecule in the bodyâs natural collagen forming process. L-ascorbic acid is a highly unstable molecule. Al-Niami, F & Chiang, N 2017. âTopical Vitamin C and the Skin: Mechanisms of Action and Clinical Applicationsâ, The Journal of Clinical and Aesthetic Dermatology, vol. the good: Helps to maintain skin barrier integrity, fights pigmentation, may be involved in inflammation processes in the skin, is involved in collagen production, and protects against sun damage. This imbalance has been studied for its links with many diseases and its role in the aging process. Collagen forms crosslinked fibers in the deeper layers of the skin which creates a net-like structure. Ascorbic acid is the preferred form of vitamin C (by skincare brands and skincare enthusiasts), however it is a highly unstable ingredient that requires a very low pH – making it not only one of the most expensive products in your routine (since it has a very short shelf life), but also potentially irritating to use for some people. Most balanced diets will provide the body with enough vitamin C to support health.Â, However, naturally occurring sources arenât stable enough or contain enough vitamin C to be used in skincare and improve the skinâs appearance. It is a highly stable, non-irritating, patented derivative. Provides superior antioxidant protection, and reduces the appearance of dullness and fine lines. 418-425.Â What Are the Benefits of L-ascorbic Acid? 143-146.Â Studies discussed in the Journal of Clinical and Aesthetic Dermatology have outlined the benefits of topical vitamin C treatments. The product’s main claim to fame is that it includes a pure form of L-ascorbic acid in ethylated form that is extremely stable in all conditions, including in presence of water. By the end of your usage cycle, your skin will be looking younger, smoother, and firmer. Alpha-arbutin works by slowly releasing hydroquinone which in turn blocks tyrosinase activity and reduces melanin production in the skin. When this skin whitening cream is taken together with vitamin c foods, it also fastens the results delivery. L-ascorbic acid is the most abundant antioxidant in the body, but humans cannot produce it on their own unlike other mammals. For a potent concentration of ascorbic acid at a lower price, The Ordinary’s Ethylated Ascorbic Acid 15% Solution is a fan favorite. The problem with L- ascorbic acid is that it is unstable for topical application. What Is Isohexadecane? After 3-O-Ethyl-L-ascorbic acid proved that it could help in skin whitening, attaining skin smoothness, and firmness is the primary reason for the growth of its demand on the global market. In short, Ethylated Ascorbic Acid performs in similar fashion to pure Ascorbic Acid and is close in molecular weight to actual Vitamin C. Ethylated Ascorbic Acid is, I believe, the most stable form of Vitamin C used in skin care and was thus an excellent choice for the chemists at Allies of Skin. Holds Powerful Antioxidant Properties. Free radicals can accumulate and create an imbalance. 3-O-Ethyl-L-ascorbic acid is also an excellent Antioxidant, and it improves your skin firm-feeling. 8, pp. As we age, collagen production decreases. L-ascorbic acid is a powerhouse ingredient that can help improve the appearance of the skin in multiple ways, making it an ideal product to bring into any skincare regime. For those looking for a supplement that will brighten the skin and give it a beautiful touch, Vitamin C for skin will be the best remedy. Inflammation in the skin is common but some people experience it on a daily basis. For instance, the compound serves as an excellent supplement for boosting melanin formation and enhancing collagen synthesis to enhance cell repair. A serum to nourish and brighten the skin. Check on Amazon. Benefits 1. There are many cosmetic products on the market today, but where to purchase quality Antioxidants and skin whitening products is always a challenge to many people. The supplement triggers nerve cell growth, which helps in skin repair as well as brightening your skin tone. 64, is. We are a professional nutritional ingredients manufacturer and supplier of pharmaceutical chemicals, nutrition supplements and biochemical products. However, because vitamin C is unstable and might fail to deliver the desired results, taking 3-0-ethyl-L-ascorbic acid will be the best idea since its more stable and will help you attain your beauty expectations. It helps you attain even skin tone as well as diminishing wrinkles and fine lines. Ethylated ascorbic acid research shows that the drug can deliver quality results, primarily when used to improve skin health. (2015). skin, and maintain skin barrier integrity. WISEPOWDER is focusing on the research, manufacturing and innovation of ingredients for nootropic and nutrition supplements. However, when ascorbic acid is mixed with other antioxidants, it delivers quality results. Different countries that were not active in purchasing skin whitening cream like 3-O-Ethyl-L-ascorbic acid are slowly becoming regular consumers, and that is also expected to grow the overall skincare market value. Currently, topical vitamin C products are being examined for how it is involved in inflammation, wound healing and post-inflammatory linked pigmentation.Â, Skin barrier integrity 9, is. The organic skincare global market has been growing over the years, and it’s expected to grow further by over 18% in the next few years. Look for products formulated with antioxidants such as ferulic acid.Â, Concentration Both the topical and oral form are often used alongside other drugs and supplementation.Â. Ethyl ascorbic acid or 3-O-Ethyl-L-Ascorbic acid (86404-04-8) is a molecule that is produced by modifying the ascorbic acid, mostly known as Vitamin C. 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